Patient Zero (2012) poster

Patient Zero (2012)


aka Biohazard

USA. 2012.


Director/Screenplay – Brian T. Jaynes, Producers – Brian T. Jaynes & Kerri Navarro, Photography – Samuel Haun & M.J. Marcinik, Special Effects – C. Michael Jaynes & Erin Volkman, Production Design – Ryan Laepple. Production Company – Hannover House/Lionshare Pictures.


Brandon Slagle (Dr Jonathan Wright), Amanda Phillips (Jenna Barnes), Van Quattro (The Major), Carl Savering (Sheriff Klein), Natalie Wilemon (Liz), Larry Jack Dotson (Marvin Johnson), Jackey Hall (Kerri Klein)


Jonathan Wright and his fiancee Jenna Barnes wake in the morning to go to Gem Labs, the agricultural research laboratory where both of them work and he is the director of the facility. Jonathan seems distant from the plans for their upcoming wedding. What Jenna is not telling him is that she is pregnant. As they settle into their workday, they are interrupted by the emergency alarms going off. The doors are sealed and everybody is locked into the laboratory. As Jonathan determines to find the cause, they are forced to fight off the infected who have become insane killers. He confesses to Jenna that Gem Labs is not an agricultural research facility as she has been led to believe but is a front for the Department of Defense. He reveals that have been employed to develop a virus that makes people frenziedly kill everybody they come into contact with and that this has been accidentally released. They are now forced to fight for their lives against the infected crazies inside the facility. At the same time, they must now also deal with the arrival of the military who have orders to eliminate every single person inside the quarantine zone.

Patient Zero is a variation on the outbreak drama. The idea of the bioweapon/contamination outbreak that causes everybody to go crazy dates back to George Romero’s original The Crazies (1973) and has played out in a number of other films. In fact, Patient Zero often reminds a good deal of the forgotten and overlooked Warning Sign (1985) about a viral outbreak at a bioresearch facility that turns the staff uncontrollably homicidal. That is to say, Patient Zero plays as a far more lower-budgeted version of Warning Sign – and one that has been more than clearly drawn from the recent success of 28 Days Later (2002).

The one thing you have to commend director Brian T. Jaynes for is that he gives the appearance of having gone away and researched his biological and laboratory procedures and makes these seem convincing. The main problem Patient Zero has is that Jaynes does nothing remarkable with the scenes of the outbreak, people being attacked by crazed infectees or the attempts to escape the facility.

Brandon Slagle trapped inside a biological containment facility in Patient Zero (2012)
Brandon Slagle trapped inside a biological containment facility with infected crazies

The scenes with the military eliminating everybody have a certain ruthlessness but you cannot help but feel that if the film had been made on a studio budget these scenes would have been given more of a dramatic intensity. Indeed, the film seems to invest more in the everyday scenes between Brandon Slagle and his fiancee Amanda Phillips than it does the action/horror element. The finished film hails in at a surprisingly short 68 minutes.

The film should not be confused with the later, better-budgeted Patient Zero (2018) about people infected with a rabies plague.

Brian T. Jaynes has made a number of other low-budget films as director and producer. He has directed other genre items such as Boggy Creek (2010), Humans vs Zombies (2011), The Underneath (2013), Bigfoot Wars (2014) and Shadow People (2016), as well as produced Hostage (2013), Jet Stream (2013), Supercollider (2013) and Dead Sea (2014). His lead actor Brandon Slagle has also directed a number of films including Area 51 Confidential (2011), The Black Dahlia Haunting (2012), Dead Sea (2014), House of Manson (2014), Crossbreed (2019), The Dawn (2019) and Attack of the Unknown (2020).

Trailer here

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